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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPTOR
All Species:
36.06
Human Site:
S599
Identified Species:
72.12
UniProt:
Q8N122
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N122
NP_065812.1
1335
149038
S599
R
W
C
G
V
R
D
S
A
H
E
K
L
Y
S
Chimpanzee
Pan troglodytes
XP_001161716
1335
149161
S599
R
W
C
G
V
R
D
S
A
H
E
K
L
Y
S
Rhesus Macaque
Macaca mulatta
XP_001110471
1335
148870
S599
R
W
C
G
V
R
D
S
A
H
E
K
L
Y
S
Dog
Lupus familis
XP_850487
1335
149172
S599
R
W
C
G
V
R
D
S
A
H
E
K
L
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q0
1335
149453
S599
R
W
C
G
V
R
D
S
A
H
E
K
L
Y
S
Rat
Rattus norvegicus
NP_001127971
1335
149475
S599
R
W
C
G
V
R
D
S
A
H
E
K
L
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426232
1335
149895
S599
R
W
C
G
V
R
D
S
A
H
E
K
L
Y
S
Frog
Xenopus laevis
NP_001088177
1334
149513
S597
R
W
C
G
V
R
D
S
A
H
E
K
L
Y
S
Zebra Danio
Brachydanio rerio
XP_001919288
1332
149175
S599
R
W
C
G
V
R
D
S
A
H
E
K
L
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624060
1279
144157
A551
Y
R
P
G
Q
I
A
A
N
H
G
S
L
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323654
1366
149968
D620
C
L
G
K
L
W
E
D
F
T
E
A
Q
M
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38873
1557
177591
L739
K
N
C
F
S
L
E
L
V
N
K
L
C
F
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.8
95.9
N.A.
96.5
96.7
N.A.
N.A.
95
90.5
87.9
N.A.
N.A.
55.5
N.A.
N.A.
Protein Similarity:
100
99.5
99.1
98.3
N.A.
98.4
98.5
N.A.
N.A.
97.6
95.9
94.6
N.A.
N.A.
70.4
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
40.8
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
58.2
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
75
0
0
9
0
0
0
% A
% Cys:
9
0
84
0
0
0
0
0
0
0
0
0
9
9
0
% C
% Asp:
0
0
0
0
0
0
75
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
17
0
0
0
84
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
9
0
0
0
0
9
0
% F
% Gly:
0
0
9
84
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
9
0
0
0
0
0
0
9
75
0
0
0
% K
% Leu:
0
9
0
0
9
9
0
9
0
0
0
9
84
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
75
9
0
0
0
75
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
75
0
0
0
9
0
0
84
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
75
0
0
0
9
0
0
0
0
9
0
% V
% Trp:
0
75
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
67
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _